ADJ. large, major, serious | fresh, further, new | occasional, periodic, sporadic | recurrent, repeated | sudden | cholera, salmonella, etc.
VERB + OUTBREAK lead to the events that led to the outbreak of World War I
OUTBREAK + VERB occur
PREP. ~ of A new outbreak of smallpox occurred in 1928.
PHRASES an outbreak of disease, an outbreak of rain, an outbreak of war/fighting/hostilities/violence