ADJ. black, bleak, deep | complete, total, utter
VERB + DESPAIR feel | drive sb to The novel tells the story of a teenager driven to despair by the hypocrisy of the adult world.
PREP. in ~ Robert shook his head in despair. | of ~ She let out a cry of despair. | with ~ He cried out with despair. | ~ at I felt despair at being deceived.
PHRASES the depths of despair When he became ill he sank to the depths of despair. | in a moment of despair, a feeling/sense of despair I was overcome with a feeling of utter despair.